Stimulation of collagen biosynthesis in 3T6 cells by factors extracted from experimentally injured rat liver
نویسندگان
چکیده
منابع مشابه
Biosynthesis of type IV collagen by cultured rat Schwann cells
We have obtained evidence that rat Schwann cells synthesize and secrete type IV procollagen. Metabolic labeling of primary cultures of Schwann cells plus neurons and analysis by SDS PAGE revealed the presence of a closely spaced pair of polypeptides in the medium of these cultures that (a) were susceptible to digestion by purified bacterial collagenase, (b) co-migrated with type IV procollagen ...
متن کاملStimulation of collagen biosynthesis by topically applied vitamin C.
In the dermis, vitamin C is required for the formation of hydroxyprolyl residues to form stable triple-helical collagen molecules, and hydroxylysyl residues operating in crosslinks synthesis. In fibroblasts culture, vitamin C is also known to stabilize the collagen messenger RNAs (m-RNA) and increase procollagen synthesis. The activity in the dermis of vitamin C topically applied on normal huma...
متن کاملBiosynthesis of Ferritin by Rat Liver Slices.
Iron greatly accelerates the biosynthesis of the protein moiety of the iron storage protein ferritin (1, 2). This phenomenon is therefore of general interest as an example of the adaptive control of specific protein synthesis. As a possible tool for studying the process in vitro, rat liver slices were tested for their ability to incorporate labeled amino acids into ferritin. In this report we d...
متن کاملEnhancement of liver size by stimulation of intact rat liver with exogenous hepatotrophic factors.
In mammals, liver size is related to animal body weight at the 2.5 to 3% proportion, a ratio mediated by the afflux of hepatotrophic factors. Formulas capable of modifying this ratio have been developed in previous studies on the rat, with enhancement of liver size brought about by intraperitoneal (portal) infusion of exogenous factors such as glucose, amino acids, insulin, glucagon, vitamins, ...
متن کاملBiosynthesis of serum albumin in rat liver. Isolation and probable structure of 'proalbumin' from rat liver.
1. Two methods are described for the preparation of 'proalbumin' in good yields from rat liver. 2. One of the methods does not depend on the use of specific antisera. 3. The product from both methods is identical as judged by electrophoresis on polyacrylamide gel, isoelectric focusing on pH gradients, ion-exchange chromatography and quantitative immunoelectrophoresis. The protein also appears t...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Kanzo
سال: 1977
ISSN: 0451-4203,1881-3593
DOI: 10.2957/kanzo.18.721